Advances in Gene Therapy for Diseases of the Eye
Author:
Affiliation:
1. Department of Ophthalmology and Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts.
2. Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hum.2016.040
Reference198 articles.
1. G Proteins and Phototransduction
2. OUTCOME MEASURES AND THEIR APPLICATION IN CLINICAL TRIALS FOR RETINAL DEGENERATIVE DISEASES
3. RPE65 is the isomerohydrolase in the retinoid visual cycle
4. Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle
5. Genetic deletion of S-opsin prevents rapid cone degeneration in a mouse model of Leber congenital amaurosis
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