Improved Production and Purification of Minicircle DNA Vector Free of Plasmid Bacterial Sequences and Capable of Persistent Transgene ExpressionIn Vivo
Author:
Affiliation:
1. Department of Pediatrics and Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hum.2005.16.126
Reference22 articles.
1. Transfection of Escherichia coli spheroplasts. V. Activity of recBC nuclease in rec+ and rec minus spheroplasts measured with different forms of bacteriophage DNA
2. Linear DNAs Concatemerize in Vivo and Result in Sustained Transgene Expression in Mouse Liver
3. Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo
4. Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo
5. A new DNA vehicle for nonviral gene delivery: supercoiled minicircle
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