Mutations in RHOT1 Disrupt Endoplasmic Reticulum–Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease-Reference-Cited by-同舟云学术

Mutations in RHOT1 Disrupt Endoplasmic Reticulum–Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease

Published:2019-12-01 Issue:16 Volume:31 Page:1213-1234
ISSN:1523-0864
Container-title:Antioxidants & Redox Signaling
language:en
Short-container-title:Antioxidants & Redox Signaling

Author:

Grossmann Dajana¹,Berenguer-Escuder Clara¹,Bellet Marie Estelle¹,Scheibner David²,Bohler Jill¹,Massart Francois¹,Rapaport Doron³,Skupin Alexander¹⁴,Fouquier d'Hérouël Aymeric¹,Sharma Manu⁵,Ghelfi Jenny¹,Raković Aleksandar⁶,Lichtner Peter⁷,Antony Paul¹,Glaab Enrico¹,May Patrick¹,Dimmer Kai Stefan³,Fitzgerald Julia Catherine²,Grünewald Anne¹⁶,Krüger Rejko¹²⁸

Affiliation:

1. Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg.

2. Department of Neurodegenerative Diseases, Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

3. Interfaculty Institute of Biochemistry (IFIB), University of Tübingen, Tübingen, Germany.

4. National Biomedical Computation Resource, University of California San Diego, La Jolla, California.

5. Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany.

6. Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.

7. Institute of Human Genetics, Helmholtz Zentrum München GmbH, Neuherberg, Germany.

8. Parkinson Research Clinic, Centre Hospitalier de Luxembourg (CHL), Luxembourg, Luxembourg.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

Link

https://www.liebertpub.com/doi/pdf/10.1089/ars.2018.7718

Reference51 articles.

1. Genetic Screening of the Mitochondrial Rho GTPases MIRO1 and MIRO2 in Parkinson's Disease

2. Regulation of ER-mitochondria contacts by Parkin via Mfn2

3. Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase

4. Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis

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