Characteristics of an scFv Antibody Fragment That Binds to Immunoglobulin G of Graves' Disease Patients and Inhibits Autoantibody-Mediated Thyroid-Stimulating Activity-Reference-Cited by-同舟云学术

Characteristics of an scFv Antibody Fragment That Binds to Immunoglobulin G of Graves' Disease Patients and Inhibits Autoantibody-Mediated Thyroid-Stimulating Activity

Published:2008-12 Issue:6 Volume:27 Page:445-451
ISSN:1554-0014
Container-title:Hybridoma
language:en
Short-container-title:Hybridoma

Author:

Zhao Yu¹,Wang Su-Li²,Li Qiang¹,Ye Jing³,Chen Kun-Ming⁴,Tian En-Jiang⁴,Chen Zu-Pei⁴

Affiliation:

1. Department of Endocrinology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.

2. Department of Endocrinology, Pingjin Hospital, Medical College of Armed Police Forces, Tianjin, China.

3. Department of Pathology, Tianjin Medical University, Tianjin, China.

4. The Endocrinology Research Institution, Tianjin Medical University, Tianjin, China.

Publisher

Mary Ann Liebert Inc

Subject

Immunology,Immunology and Allergy

Link

http://www.liebertpub.com/doi/pdf/10.1089/hyb.2008.0045

Reference28 articles.

1. Stimulating and Blocking Thyroid-Stimulating Hormone (TSH) Receptor Autoantibodies from Patients with Graves’ Disease and Autoimmune Hypothyroidism Have Very Similar Concentration, TSH Receptor Affinity, and Binding Sites

2. Estimation of Serum TSH Receptor Autoantibody Concentration and Affinity

3. Engineering the Human Thyrotropin Receptor Ectodomain from a Non-secreted Form to a Secreted, Highly Immunoreactive Glycoprotein That Neutralizes Autoantibodies in Graves' Patients' Sera

4. Human immunoglobulin G autoantibodies to the thyrotropin receptor from Epstein-Barr virus-transformed B lymphocytes: characterization by immunoprecipitation with recombinant antigen and biological activity

5. Thyroid-Stimulating Monoclonal Antibodies