An Oncolytic Adenovirus Targeting Transforming Growth Factor β Inhibits Protumorigenic Signals and Produces Immune Activation: A Novel Approach to Enhance Anti-PD-1 and Anti-CTLA-4 Therapy-Reference-Cited by-同舟云学术

An Oncolytic Adenovirus Targeting Transforming Growth Factor β Inhibits Protumorigenic Signals and Produces Immune Activation: A Novel Approach to Enhance Anti-PD-1 and Anti-CTLA-4 Therapy

Published:2019-09-01 Issue:9 Volume:30 Page:1117-1132
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Yang Yuefeng¹²,Xu Weidong¹,Peng Di³,Wang Hao²,Zhang Xiaoyan²,Wang Hua²,Xiao Fengjun²,Zhu Yitan⁴,Ji Yuan⁴,Gulukota Kamalakar⁵,Helseth Donald L.⁵,Mangold Kathy A.⁶,Sullivan Megan⁶,Kaul Karen⁶,Wang Edward⁷,Prabhakar Bellur S.⁸,Li Jinnan³,Wu Xuejie³,Wang Lisheng²,Seth Prem¹

Affiliation:

1. Gene Therapy Program, Department of Medicine, NorthShore Research Institute, an Affiliate of the University of Chicago, Evanston, Illinois

2. Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing, China

3. Department of Urology, The Third Medical Center of Chinese People's Liberation Army, Beijing, China

4. Program of Computational Genomics and Medicine, Department of Surgery; NorthShore University HealthSystem, Evanston, Illinois

5. Center for Personalized Medicine, Department of Surgery; NorthShore University HealthSystem, Evanston, Illinois

6. Department of Pathology and Laboratory Medicine, NorthShore University HealthSystem, Evanston, Illinois

7. Biostatistics and Clinical Research Informatics, Department of Surgery; NorthShore University HealthSystem, Evanston, Illinois

8. Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, Illinois.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

https://www.liebertpub.com/doi/pdf/10.1089/hum.2019.059

Reference65 articles.

1. Changing Treatment Paradigms in Metastatic Breast Cancer

2. TGFβ in Cancer

3. TGF-β signaling and epithelial–mesenchymal transition in cancer progression

4. Targeting TGF-β Signaling for Therapeutic Gain

Cited by 40 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Revolutionizing Cancer Treatment: Unleashing the Power of Combining Oncolytic Viruses with CAR-T Cells;Anti-Cancer Agents in Medicinal Chemistry;2024-07-24

2. Viral and Non-Viral Systems to Deliver Gene Therapeutics to Clinical Targets;International Journal of Molecular Sciences;2024-07-04

3. Intratumoral delivery of immunotherapy to treat breast cancer: current development in clinical and preclinical studies;Frontiers in Immunology;2024-05-13

4. Oncolytic virus-based combination therapy in breast cancer;Cancer Letters;2024-03

5. Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy;Molecular Biology Reports;2024-01-28