A Phase 2 Study to Evaluate the Safety and Immunogenicity of a Recombinant HIV Type 1 Vaccine Based on Adeno-Associated Virus-Reference-Cited by-同舟云学术

A Phase 2 Study to Evaluate the Safety and Immunogenicity of a Recombinant HIV Type 1 Vaccine Based on Adeno-Associated Virus

Published:2010-08 Issue:8 Volume:26 Page:933-942
ISSN:0889-2229
Container-title:AIDS Research and Human Retroviruses
language:en
Short-container-title:AIDS Research and Human Retroviruses

Author:

Vardas Eftyhia¹,Kaleebu Pontiano²³,Bekker Linda-Gail⁴,Hoosen Anwar⁵,Chomba Elwyn⁶,Johnson Philip R.⁷,Anklesaria Pervin⁸,Birungi Josephine²,Barin Burc⁹,Boaz Mark¹⁰,Cox Josephine¹¹,Lehrman Jennifer¹¹,Stevens Gwynn¹²,Gilmour Jill¹⁰,Tarragona Tony¹⁰,Hayes Peter¹⁰,Lowenbein Sarah¹⁰,Kizito Eva¹⁰,Fast Patricia¹¹,Heald Alison E.⁸,Schmidt Claudia¹¹

Affiliation:

1. Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, Soweto, South Africa.

2. Uganda Virus Research Institute—International AIDS Vaccine Initiative (UVRI-IAVI) HIV Vaccine Program, Entebbe, Uganda.

3. MRC-UVRI Uganda Research Unit on AIDS, Entebbe, Uganda.

4. Desmond Tutu HIV Centre, Cape Town, South Africa.

5. Department of Medical Microbiology, Medunsa, Pretoria, South Africa.

6. Zambia Emory HIV Research Program, Lusaka, Zambia.

7. The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104 and Columbus Children's Research Institute, Columbus, Ohio.

8. Targeted Genetics Corporation, Seattle, Washington.

9. The EMMES Corporation, Rockville, Maryland.

10. International AIDS Vaccine Initiative, Human Immunology Laboratory, Imperial College, London, UK.

11. International AIDS Vaccine Initiative, New York, New York.

12. IAVI Southern Africa Regional Office, Johannesburg, South Africa.

Publisher

Mary Ann Liebert Inc

Subject

Infectious Diseases,Virology,Immunology

Link

http://www.liebertpub.com/doi/pdf/10.1089/aid.2009.0242

Reference10 articles.

1. Worldwide Epidemiology of Neutralizing Antibodies to Adeno‐Associated Viruses

2. Genetic Fate of Recombinant Adeno-Associated Virus Vector Genomes in Muscle

3. Characterization of Adeno-Associated Virus Genomes Isolated from Human Tissues

4. Novel Adeno-Associated Virus Vector Vaccine Restricts Replication of Simian Immunodeficiency Virus in Macaques

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