A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function-Reference-Cited by-同舟云学术

A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function

Published:2018-05 Issue:5 Volume:37 Page:449-456
ISSN:1044-5498
Container-title:DNA and Cell Biology
language:en
Short-container-title:DNA and Cell Biology

Author:

Cui Xiukun¹,Zhou Zheng¹,Zhu Keke²,Feng Ruiping¹,Han Jiuli¹,Li Mengyuan¹,Wang Shuangfeng¹,Li Jing¹,Zhang Jing¹,Jiang Qiying¹,Zhang Wanting²,Mu Hongmei²,Liu Yutao³,Hu Yanzhong¹²

Affiliation:

1. Joint National Laboratory for Antibody Drug Engineering, Henan International Union Laboratory of Antibody Medicine, Department of Cell Biology and Genetics, Henan University School of Medicine, Kaifeng, China.

2. Kaifeng Key Lab of Cataract and Myopia, Institute of Eye Diseases, Kaifeng Centre Hospital, Kaifeng, China.

3. Department of Cell Biology and Anatomy, Augusta University, Augusta, Georgia.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Genetics,Molecular Biology,General Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/dna.2017.4051

Reference32 articles.

1. Connexin mutation that causes dominant congenital cataracts inhibits gap junctions, but not hemichannels, in a dominant negative manner

2. Connexins modulate autophagosome biogenesis

3. The Cataract-linked Mutant Connexin50D47A Causes Endoplasmic Reticulum Stress in Mouse Lenses