1. Department of Pharmacology, Merck Research Laboratories, Boston, Massachusetts, and West Point, Pennsylvania.
2. Department of Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Merck Research Laboratories, Boston, Massachusetts, and West Point, Pennsylvania.
3. Center for Applied and Computational Mathematics, Rochester Institute of Technology, Rochester, New York.
4. Department of Discovery Pharmaceutical Sciences, Merck Research Laboratories, Boston, Massachusetts, and West Point, Pennsylvania.
5. Discovery Research Services Charles River Laboratories, Senneville, Quebec, Canada.
6. Department of Safety Assessment and Laboratory Animal Sciences, Merck Research Laboratories, Boston, Massachusetts, and West Point, Pennsylvania.
7. Department of Biology Discovery, Merck Research Laboratories, Boston, Massachusetts, and West Point, Pennsylvania.