Btk Inhibitor RN983 Delivered by Dry Powder Nose-only Aerosol Inhalation Inhibits Bronchoconstriction and Pulmonary Inflammation in the Ovalbumin Allergic Mouse Model of Asthma-Reference-Cited by-同舟云学术

Btk Inhibitor RN983 Delivered by Dry Powder Nose-only Aerosol Inhalation Inhibits Bronchoconstriction and Pulmonary Inflammation in the Ovalbumin Allergic Mouse Model of Asthma

Published:2016-06 Issue:3 Volume:29 Page:233-241
ISSN:1941-2711
Container-title:Journal of Aerosol Medicine and Pulmonary Drug Delivery
language:en
Short-container-title:Journal of Aerosol Medicine and Pulmonary Drug Delivery

Author:

Phillips Jonathan E.¹,Renteria Lorena¹,Burns Lisa¹,Harris Paul¹,Peng Ruoqi¹,Bauer Carla M.T.¹,Laine Dramane¹,Stevenson Christopher S.¹

Affiliation:

1. Hoffmann-La Roche Inc., Pharma Research and Early Development, DTA Inflammation, Nutley, New Jersey.

Publisher

Mary Ann Liebert Inc

Subject

Pharmacology (medical),Pharmaceutical Science,Pulmonary and Respiratory Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/jamp.2015.1210

Reference48 articles.

1. A thousand and one protein kinases

2. RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents

3. The Primary Immunodeficiencies

4. Serum IgE clearance is facilitated by human FcεRI internalization

5. Btk Plays a Crucial Role in the Amplification of FcϵRI-mediated Mast Cell Activation by Kit

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