Quantitative Assessment of Mucociliary Clearance in Smokers with Mild-to-Moderate Chronic Obstructive Pulmonary Disease and Chronic Bronchitis from Planar Radionuclide Imaging Using the Change in Penetration Index-Reference-Cited by-同舟云学术

Quantitative Assessment of Mucociliary Clearance in Smokers with Mild-to-Moderate Chronic Obstructive Pulmonary Disease and Chronic Bronchitis from Planar Radionuclide Imaging Using the Change in Penetration Index

Published:2019-08 Issue:4 Volume:32 Page:175-188
ISSN:1941-2711
Container-title:Journal of Aerosol Medicine and Pulmonary Drug Delivery
language:en
Short-container-title:Journal of Aerosol Medicine and Pulmonary Drug Delivery

Author:

Fleming John S.¹²,Conway Joy¹³,Bennett Michael J.¹,Tossici-Bolt Livia²,Guy Matthew²,Blé François-Xavier⁴,McCrae Christopher⁵,Carlsson Mats⁶,Bondesson Eva⁷

Affiliation:

1. National Institute of Health Research Biomedical Research Unit in Respiratory Disease, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.

2. Department of Medical Physics, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.

3. Faculty of Health Sciences, University of Southampton, Southampton, United Kingdom.

4. Precision Medicine and Genomics, Innovative Medicines and Early Development, AstraZeneca, Royston, United Kingdom.

5. Respiratory Inflammation and Autoimmunity (RIA) Innovative Medicines and Early Development Unit, AstraZeneca Gothenburg, Mölndal, Sweden.

6. Global Medicines Development, AstraZeneca Gothenburg, Mölndal, Sweden.

7. Clinical Studies Sweden, Forum South, Skane University Hospital, Lund, Sweden.

Publisher

Mary Ann Liebert Inc

Subject

Pharmacology (medical),Pharmaceutical Science,Pulmonary and Respiratory Medicine

Link

https://www.liebertpub.com/doi/pdf/10.1089/jamp.2017.1441

Reference41 articles.

1. Chronic obstructive pulmonary disease: molecular and cellularmechanisms

2. Mucus Clearance and Lung Function in Cystic Fibrosis with Hypertonic Saline

3. Lung mucociliary clearance

4. Beneficial effect of inhaled mannitol and cough in asthmatics with mucociliary dysfunction

5. Mucociliary clearance in COPD can be increased by both a D2/β2 and a standard β2 agonists

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