Detrimental Effects of an Inhaled Phosphodiesterase-4 Inhibitor on Lung Inflammation in Ventilated Preterm Lambs Exposed to Chorioamnionitis Are Dose Dependent-Reference-Cited by-同舟云学术

Detrimental Effects of an Inhaled Phosphodiesterase-4 Inhibitor on Lung Inflammation in Ventilated Preterm Lambs Exposed to Chorioamnionitis Are Dose Dependent

Published:2019-12-01 Issue:6 Volume:32 Page:396-404
ISSN:1941-2711
Container-title:Journal of Aerosol Medicine and Pulmonary Drug Delivery
language:en
Short-container-title:Journal of Aerosol Medicine and Pulmonary Drug Delivery

Author:

Hütten Matthias C.¹²,Fehrholz Markus²,Konrad Franziska M.³,Ophelders Daan¹,Kleintjes Clementine¹,Ottensmeier Barbara²,Spiller Owen Brad⁴,Glaser Kirsten²,Kramer Boris W.¹,Kunzmann Steffen²⁵

Affiliation:

1. Neonatology, Pediatrics Department, Faculty of Health, Medicine and Life Sciences, Maastricht University Medical Center, Maastricht, The Netherlands.

2. University Children's Hospital Würzburg, University of Würzburg, Würzburg, Germany.

3. Department of Anesthesiology and Intensive Care Medicine, University Hospital of Tübingen, Tübingen, Germany.

4. Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.

5. Clinic of Neonatology, Bürgerhospital Frankfurt am Main, Frankfurt, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Pharmacology (medical),Pharmaceutical Science,Pulmonary and Respiratory Medicine

Link

https://www.liebertpub.com/doi/pdf/10.1089/jamp.2019.1528

Reference39 articles.

1. Mechanisms of Lung Injury and Bronchopulmonary Dysplasia

2. Thrown off balance: the effect of antenatal inflammation on the developing lung and immune system

3. Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infants

4. Can the preterm lung recover from perinatal stress?

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1. Acute Lung Functional and Airway Remodeling Effects of an Inhaled Highly Selective Phosphodiesterase 4 Inhibitor in Ventilated Preterm Lambs Exposed to Chorioamnionitis;Pharmaceuticals;2022-12-26

2. Screening of Chorioamnionitis Using Volatile Organic Compound Detection in Exhaled Breath: A Pre-clinical Proof of Concept Study;Frontiers in Pediatrics;2021-05-26

3. Aerosol drug delivery to spontaneously-breathing preterm neonates: lessons learned;Respiratory Research;2021-02-26

4. Spatiotemporal Changes in the Gene Expression Spectrum of the β2 Adrenergic Receptor Signaling Pathway in the Lungs of Rhesus Monkeys;Lung;2021-01-29

5. Pathophysiological effects of intravenous phosphodiesterase type 4 inhibitor in addition to surfactant lavage in meconium‐injured newborn piglet lungs;Pediatric Pulmonology;2020-06-19