Valved Holding Chambers and In Vitro Metered Dose Inhaler Performance: Effects of Flow Rate and Inhalation Delay

Author:

Liu Xiaofei1,Guo Changning1,Chowdhury Badrul2,Starke Peter2,Limb Susan3,Peri Prasad4,Schroeder Alan5,Doub William6

Affiliation:

1. Division of Pharmaceutical Analysis, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, St. Louis, Missouri.

2. Division of Pulmonary, Allergy and Rheumatology Products, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.

3. Division of Pulmonary, Allergy and Rheumatology Products, Center for Drug Evaluation and Research, Formally U.S. Food and Drug Administration, Silver Spring, Maryland (currently Genentech).

4. Office of New Drug Quality Assessment, Center for Drug Evaluation and Research, Formally U.S. Food and Drug Administration, Silver Spring, Maryland (currently Teva).

5. Office of New Drug Quality Assessment, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland (Retired).

6. Division of Pharmaceutical Analysis, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, St. Louis, Missouri (Retired).

Publisher

Mary Ann Liebert Inc

Subject

Pharmacology (medical),Pharmaceutical Science,Pulmonary and Respiratory Medicine

Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Optimal Inhalation Profile of Pressurized Metered Dry Powder Inhaler Using a Valved Holding Chamber: A Dynamic Analysis;Journal of Aerosol Medicine and Pulmonary Drug Delivery;2024-06-01

2. Influence of the valve on the performance of two cylindrical valved holding chambers;Powder Technology;2023-01

3. Pulmonary;Practical Pharmaceutics;2023

4. Design of Experiments for the Development of Inhalational Products;Design of Experiments for Pharmaceutical Product Development;2021

5. Metered dose inhalers (MDIs);Inhaled Medicines;2021

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