Pharmacokinetics and Pharmacodynamics of Fluticasone Propionate and Salmeterol Delivered as a Combination Dry Powder from a Capsule-Based Inhaler and a Multidose Inhaler in Asthma and COPD Patients-Reference-Cited by-同舟云学术

Pharmacokinetics and Pharmacodynamics of Fluticasone Propionate and Salmeterol Delivered as a Combination Dry Powder from a Capsule-Based Inhaler and a Multidose Inhaler in Asthma and COPD Patients

Published:2014-08 Issue:4 Volume:27 Page:279-289
ISSN:1941-2711
Container-title:Journal of Aerosol Medicine and Pulmonary Drug Delivery
language:en
Short-container-title:Journal of Aerosol Medicine and Pulmonary Drug Delivery

Author:

Daley-Yates Peter T.¹,Mehta Rashmi²,Chan Robert H.¹,Despa Simona X.²,Louey Margaret D.²

Affiliation:

1. GlaxoSmithKline, Stockley Park, Uxbridge, UK.

2. GlaxoSmithKline, Research Triangle Park, NC.

Publisher

Mary Ann Liebert Inc

Subject

Pharmacology (medical),Pharmaceutical Science,Pulmonary and Respiratory Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/jamp.2013.1040

Reference10 articles.

1. Pharmacokinetic, pharmacodynamic, efficacy, and safety data from two randomized, double-blind studies in patients with asthma and an in vitro study comparing two dry-powder inhalers delivering a combination of salmeterol 50 μg and fluticasone propionate 250 μg: Implications for establishing bioequivalence of inhaled products

2. Systemic bioavailability of hydrofluoroalkane (HFA) formulations of fluticasone/salmeterol in healthy volunteers via pMDI alone and spacer

3. Establishing bioequivalence for inhaled drugs; weighing the evidence

4. Role of Pharmacokinetics in Establishing Bioequivalence for Orally Inhaled Drug Products: Workshop Summary Report

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