Hepatic Spheroids for Long-Term Toxicity Studies-Reference-Cited by-同舟云学术

Hepatic Spheroids for Long-Term Toxicity Studies

Published:2016-12 Issue:4 Volume:2 Page:185-196
ISSN:2332-1512
Container-title:Applied In Vitro Toxicology
language:en
Short-container-title:Applied In Vitro Toxicology

Author:

Jakubek Lorin M.¹,Ulinski Greg²,Leite Daniela³,Slavsky Marina⁴,Rajanna Shibhani¹,Morelli James¹,Kelly Megan¹,Dwyer Jacquelyn¹,Fitzgerald Maria⁴,Piepenhagen Peter²,Jayyosi Zaid¹

Affiliation:

1. Predictive and Investigative Toxicology, Sanofi US, Framingham, Massachusetts.

2. Pathology, Genzyme, Framingham, Massachusetts.

3. CIEnP—Centro de Inovacao e Ensaios Pre Clinicos, Florianopolis, Brazil.

4. Drug Metabolism and Pharmacokinetics, Sanofi US, Waltham, Massachusetts.

Publisher

Mary Ann Liebert Inc

Subject

Health, Toxicology and Mutagenesis,Medical Laboratory Technology,Toxicology

Link

http://www.liebertpub.com/doi/pdf/10.1089/aivt.2016.0016

Reference44 articles.

1. Pre-Clinical Assessment of the Potential Intrinsic Hepatotoxicity of Candidate Drugs

2. Current Concepts of Mechanisms in Drug-Induced Hepatotoxicity

3. Three-dimensional culture of hepatocytes for prediction of drug-induced hepatotoxicity

4. Priorities and standards in pharmacogenetic research

5. Molecular Mechanisms Underlying the Dedifferentiation Process of Isolated Hepatocytes and Their Cultures

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1. Characterization of a long-term mouse primary liver 3D tissue model recapitulating innate-immune responses and drug-induced liver toxicity;PLOS ONE;2020-07-09

2. Engineering HepG2 spheroids with injectable fiber fragments as predictable models for drug metabolism and tumor infiltration;Journal of Biomedical Materials Research Part B: Applied Biomaterials;2020-07-05

3. Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines;Nature Communications;2020-03-13

4. An Automated Multiplexed Hepatotoxicity and CYP Induction Assay Using HepaRG Cells in 2D and 3D;SLAS DISCOVERY: Advancing the Science of Drug Discovery;2017-03-27

5. Progress Toward Understanding Drug-Induced Liver Injury;Applied In Vitro Toxicology;2016-12