Avoiding False Positives and Optimizing Identification of True Negatives in Estrogen Receptor Binding and Agonist/Antagonist Assays-Reference-Cited by-同舟云学术

Avoiding False Positives and Optimizing Identification of True Negatives in Estrogen Receptor Binding and Agonist/Antagonist Assays

Published:2017-06 Issue:2 Volume:3 Page:163-181
ISSN:2332-1512
Container-title:Applied In Vitro Toxicology
language:en
Short-container-title:Applied In Vitro Toxicology

Author:

Hornung Michael W.¹,Tapper Mark A.¹,Denny Jeffrey S.¹,Sheedy Barbara R.¹,Erickson Raymond¹,Sulerud Taylor J.¹,Kolanczyk Richard C.¹,Schmieder Patricia K.¹

Affiliation:

1. US Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, Duluth, Minnesota.

Publisher

Mary Ann Liebert Inc

Subject

Health, Toxicology and Mutagenesis,Medical Laboratory Technology,Toxicology

Link

http://www.liebertpub.com/doi/pdf/10.1089/aivt.2016.0021

Reference28 articles.

1. Issues Arising When Interpreting Results from an in Vitro Assay for Estrogenic Activity

2. Screening for estrogenicity and anti-estrogenicity: a critical evaluation of an MVLN cell-based transactivation assay

3. Use of Trout Liver Slices To Enhance Mechanistic Interpretation of Estrogen Receptor Binding for Cost-Effective Prioritization of Chemicals within Large Inventories

4. Effects-based chemical category approach for prioritization of low affinity estrogenic chemicals

5. A rule-based expert system for chemical prioritization using effects-based chemical categories

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