Non-Invasive Vagus Nerve Stimulation Improves Brain Lesion Volume and Neurobehavioral Outcomes in a Rat Model of Traumatic Brain Injury

Author:

Divani Afshin A.1,Salazar Pascal2,Ikram Hafiz A.1,Taylor Erik3,Wilson Colin M.3,Yang Yirong4,Mahmoudi Javad5,Seletska Alina1,SantaCruz Karen S.6,Torbey Michel T.1,Liebler Eric J.7,Bragina Olga A.8,Morton Russel A.9,Bragin Denis E.8

Affiliation:

1. Department of Neurology, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.

2. Canon Medical Informatics, Inc., Minnetonka, Minnesota, USA.

3. Department of Radiology, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.

4. Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.

5. Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

6. Department of Pathology, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.

7. electroCore, Inc., Rockaway, New Jersey, USA.

8. Lovelace Biomedical Research Institute, Albuquerque, New Mexico, USA.

9. Department of Neuroscience, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.

Publisher

Mary Ann Liebert Inc

Subject

Neurology (clinical)

Reference58 articles.

1. Inflammation and Neuroprotection in Traumatic Brain Injury

2. 2. Centers for Disease Control and Prevention. Report to Congress on Traumatic Brain Injury in the United States: Epidemiology and Rehabilitation. Atlanta: National Center for Injury Prevention and Control, Division of Unintentional Injury Prevention; 2014.

3. Traumatic brain injury in the United States: an epidemiologic overview

4. Brain trauma elicits non-canonical macrophage activation states

5. Surgically implanted and non‐invasive vagus nerve stimulation: a review of efficacy, safety and tolerability

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