Allele-Selective Inhibition of Mutant Huntingtin with 2-Thio- and C5- Triazolylphenyl-Deoxythymidine-Modified Antisense Oligonucleotides
Author:
Affiliation:
1. Isis Pharmaceuticals, Carlsbad, California.
2. Department of Physics, Chemistry and Pharmacy, Nucleic Acid Center, University of Southern Denmark, Odense, Denmark.
3. Department of Chemistry, Kurukshetra University, Kurukshetra, India.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry
Link
http://www.liebertpub.com/doi/pdf/10.1089/nat.2015.0547
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1. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
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