Pharmacokinetic Profile and Acute Toxicological Properties of a Novel Radiosensitizer Cytosine–Phosphate–Guanosine Oligodeoxynucleotide 107 in Mice Following Intravenous and Orthotopic Administration-Reference-Cited by-同舟云学术

Pharmacokinetic Profile and Acute Toxicological Properties of a Novel Radiosensitizer Cytosine–Phosphate–Guanosine Oligodeoxynucleotide 107 in Mice Following Intravenous and Orthotopic Administration

Published:2015-10 Issue:5 Volume:25 Page:254-265
ISSN:2159-3337
Container-title:Nucleic Acid Therapeutics
language:en
Short-container-title:Nucleic Acid Therapeutics

Author:

Cen Yanyan¹,Li Xiaoli¹,Yin Zhiwei²,Yan Zifei¹,Liu Dan¹,Peng Wei¹,Pan Feng³,Zhou Hong¹

Affiliation:

1. Department of Pharmacology, College of Pharmacy, The Third Military Medical University, Chongqing, People's Republic of China.

2. No. 546 Hospital of China People's Liberation Army, Urumqi, People's Republic of China.

3. Biomedical Analysis Center, The Third Military Medical University, Chongqing, People's Republic of China.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://www.liebertpub.com/doi/pdf/10.1089/nat.2015.0538

Reference44 articles.

1. Formulation of an antispasmodic drug as a topical local anesthetic

2. G3139 and Other CpG-Containing Immunostimulatory Phosphorothioate Oligodeoxynucleotides Are Potent Suppressors of the Growth of Human Tumor Xenografts in Nude Mice

3. Class C CpG oligodeoxynucleotides as a single agent and in combination with radiotherapy efficiently delayed growth of subcutaneous B16F1 tumors

4. CpG Oligodeoxynucleotide Enhances Tumor Response to Radiation

5. Successful combination of local CpG-ODN and radiotherapy in malignant glioma

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