Technology for Discovery of Antifibrotic Drugs: Phenotypic Screening for LARP6 Inhibitors Using Inverted Yeast Three Hybrid System
Author:
Affiliation:
1. Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, Florida.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
https://www.liebertpub.com/doi/pdf/10.1089/adt.2018.904
Reference46 articles.
1. Cellular and molecular mechanisms of fibrosis
2. Fibrotic disease and the TH1/TH2 paradigm
3. Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review
4. Collagen biosynthesis: A mini-review cluster
5. LARP6 Meets Collagen mRNA: Specific Regulation of Type I Collagen Expression
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2. Targeting type I collagen for cancer treatment;International Journal of Cancer;2022-03-08
3. Characterization of Sequence-Specific Binding of LARP6 to the 5′ Stem-Loop of Type I Collagen mRNAs and Implications for Rational Design of Antifibrotic Drugs;Journal of Molecular Biology;2022-01
4. Characterization of sequence specific binding of LARP6 to the 5’ stem-loop of type I collagen mRNAs and implications for rational design of antifibrotic drugs;2020-10-01
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