A Truncated Plasmid-Encoded HIV-1 Reverse Transcriptase Displays Strong Immunogenicity
Author:
Affiliation:
1. Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
2. Swedish Institute for Communicable Disease Control, Solna, Sweden.
Publisher
Mary Ann Liebert Inc
Subject
Virology,Molecular Medicine,Immunology
Link
https://www.liebertpub.com/doi/pdf/10.1089/vim.2012.0083
Reference22 articles.
1. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
2. Phase 1 Safety and Immunogenicity Testing of DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-like Particles
3. Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand
4. In Vivo Electroporation Enhances the Immunogenicity of an HIV-1 DNA Vaccine Candidate in Healthy Volunteers
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2. HIVIS-DNA or HIVISopt-DNA priming followed by CMDR vaccinia-based boosts induce both humoral and cellular murine immune responses to HIV;Heliyon;2017-06
3. Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Effects on Its Immunogenic Performance in DNA-Immunized Mice;Journal of Immunology Research;2017
4. Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme’s performance in gene immunization;Human Vaccines & Immunotherapeutics;2013-10-04
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