Leptin Potentiates BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells Through the Activation of JAK/STAT Signaling

Author:

Zhang Bo12,Yang Lijuan12,Zeng Zongyue23,Feng Yixiao24,Wang Xi23,Wu Xiaoxing24,Luo Huaxiu25,Zhang Jing24,Zhang Meng26,Pakvasa Mikhail2,Wagstaff William2,He Fang24,Mao Yukun27,Qin Kevin2,Ding Huimin28,Zhang Yongtao29,Niu Changchun210,Wu Meng12,Zhao Xia29,Wang Hao23,Huang Linjuan24,Shi Dayao211,Liu Qing212,Ni Na23,Fu Kai27,Athiviraham Aravind2,Moriatis Wolf Jennifer2,Lee Michael J.2,Hynes Kelly2,Strelzow Jason2,El Dafrawy Mostafa2,Xia Yayi1,He Tong-Chuan2

Affiliation:

1. Departments of Orthopaedic Surgery and Obstetrics and Gynecology, Institute of Bone and Joint Research, The First and Second Hospitals of Lanzhou University, Lanzhou, China.

2. Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois.

3. Ministry of Education Key Laboratory of Diagnostic Medicine, and the School of Laboratory Medicine, Chongqing Medical University, Chongqing, China.

4. Departments of Breast Surgery, Gastrointestinal Surgery, Obstetrics and Gynecology, and Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

5. Department of Burn and Plastic Surgery, West China Hospital of Sichuan University, Chengdu, China.

6. Department of Orthopaedic Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.

7. Departments of Orthopaedic Surgery and Neurosurgery, The Affiliated Zhongnan Hospital of Wuhan University, Wuhan, China.

8. Department of Orthopaedic Surgery, BenQ Medical Center Affiliated with Nanjing Medical University, Nanjing, China.

9. Department of Orthopaedic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.

10. Department of Laboratory Diagnostic Medicine, Chongqing General Hospital, Chongqing, China.

11. Department of Orthopaedic Surgery, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

12. Department of Spine Surgery, Second Xiangya Hospital, Central South University, Changsha, China.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Developmental Biology,Hematology

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