Reciprocal Regulation of Rac1 and PAK-1 by HIF-1α: A Positive-Feedback Loop Promoting Pulmonary Vascular Remodeling-Reference-Cited by-同舟云学术

Reciprocal Regulation of Rac1 and PAK-1 by HIF-1α: A Positive-Feedback Loop Promoting Pulmonary Vascular Remodeling

Published:2010-08-15 Issue:4 Volume:13 Page:399-412
ISSN:1523-0864
Container-title:Antioxidants & Redox Signaling
language:en
Short-container-title:Antioxidants & Redox Signaling

Author:

Diebold Isabel¹,Petry Andreas¹,Djordjevic Talija¹,BelAiba Rachida S.¹,Fineman Jeffrey²,Black Stephen³,Schreiber Christian⁴,Fratz Sohrab¹,Hess John¹,Kietzmann Thomas⁵,Görlach Agnes¹

Affiliation:

1. Department of Pediatric Cardiology and Congenital Heart Diseases, German Heart Center Munich at the Technical University Munich, Munich, Germany.

2. Department of Pediatrics and Cardiovascular Research Institute, UC San Francisco, San Francisco, California.

3. Vascular Biology Center, Medical College of Georgia, Augusta, Georgia.

4. Department of Cardiac Surgery, German Heart Center Munich at the Technical University Munich, Germany.

5. Faculty of Chemistry/Biochemistry, University of Kaiserslautern, Kaiserslautern, Germany, and the Department of Biochemistry, University of Oulu, Oulu, Finland.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

Link

http://www.liebertpub.com/doi/pdf/10.1089/ars.2009.3013

Reference48 articles.

1. The Serum- and Glucocorticoid-Inducible Kinase Sgk-1 Is Involved in Pulmonary Vascular Remodeling

2. Biology of the p21-Activated Kinases

3. Reactive Oxygen Species Activate the HIF-1α Promoter Via a Functional NFκB Site

4. The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression

5. Oxidative stress contributes to pulmonary hypertension in the transgenic (mRen2)27 rat

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