Cytokine-Induced Killer Cells Engineered with Exogenous T-Cell Receptors Directed Against Melanoma Antigens: Enhanced Efficacy of Effector Cells Endowed with a Double Mechanism of Tumor Recognition-Reference-Cited by-同舟云学术

Cytokine-Induced Killer Cells Engineered with Exogenous T-Cell Receptors Directed Against Melanoma Antigens: Enhanced Efficacy of Effector Cells Endowed with a Double Mechanism of Tumor Recognition

Published:2015-04 Issue:4 Volume:26 Page:220-231
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Elia Angela R.¹,Circosta Paola¹,Sangiolo Dario²³,Bonini Chiara⁴,Gammaitoni Loretta²³,Mastaglio Sara⁴,Genovese Pietro⁵,Geuna Massimo⁶,Avolio Fabio¹,Inghirami Giorgio⁷⁸,Tarella Corrado¹⁹,Cignetti Alessandro¹⁹

Affiliation:

1. Molecular Biotechnology Center, University of Torino, 10126 Turin, Italy.

2. Candiolo Cancer Institute-FPO, Istituto di Ricovero e Cura a Carattere Scientifico, 10060 Candiolo, Italy.

3. Department of Oncology, University of Torino, 10060 Turin, Italy.

4. Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, 20132 Milan, Italy.

5. TIGET, San Raffaele Telethon Institute for Gene Therapy, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy.

6. Laboratory of Immunopathology, Department of Pathology AO Ordine Mauriziano, 10128 Turin, Italy.

7. Department of Molecular Biotechnology and Health Science and Center for Experimental Research and Medical Studies, University of Torino, 10126 Turin, Italy.

8. Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065.

9. University Division of Hematology and Cell Therapy, AO Ordine Mauriziano and University of Torino, 10128 Turin, Italy.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2014.112

Reference51 articles.

1. Two pathways of exocytosis of cytoplasmic granule contents and target cell killing by cytokine-induced CD3+ CD56+ killer cells

2. Effective Activity of Cytokine-Induced Killer Cells against Autologous Metastatic Melanoma Including Cells with Stemness Features

3. Antitumor activities of human autologous cytokine-induced killer (CIK) cells against hepatocellular carcinoma cellsin vitroandin vivo

4. Cytokine-Induced Killer Cells Eradicate Bone and Soft-Tissue Sarcomas

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