Combination of BMP2 and EZH2 Inhibition to Stimulate Osteogenesis in a 3D Bone Reconstruction Model-Reference-Cited by-同舟云学术

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Combination of BMP2 and EZH2 Inhibition to Stimulate Osteogenesis in a 3D Bone Reconstruction Model

Published:2021-08-01 Issue:15-16 Volume:27 Page:1084-1098
ISSN:1937-3341
Container-title:Tissue Engineering Part A
language:en
Short-container-title:Tissue Engineering Part A

Author:

Lui Hayman¹²³,Samsonraj Rebekah M.²³,Vaquette Cedryck⁴,Denbeigh Janet²³,Kakar Sanjeev²,Cool Simon M.⁵,Dudakovic Amel²³,van Wijnen Andre J.²³

Affiliation:

1. School of Medicine, Griffith University, Gold Coast, Queensland, Australia.

2. Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

3. Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.

4. School of Dentistry, The University of Queensland, Brisbane, Queensland, Australia.

5. Glycotherapeutics Group, Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

Publisher

Mary Ann Liebert Inc

Subject

Biomedical Engineering,Biomaterials,Biochemistry,Bioengineering

Link

https://www.liebertpub.com/doi/pdf/10.1089/ten.tea.2020.0218

Reference63 articles.

1. Autologous bone graft in the treatment of post-traumatic bone defects: a systematic review and meta-analysis

2. Biological Facet of Segmental Bone Loss Reconstruction

3. Autologous Iliac Bone Graft Compared with Biphasic Hydroxyapatite and Calcium Sulfate Cement for the Treatment of Bone Defects in Tibial Plateau Fractures

4. The available evidence on demineralised bone matrix in trauma and orthopaedic surgery

5. Design, Materials, and Mechanobiology of Biodegradable Scaffolds for Bone Tissue Engineering

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1. Role of histone methyltransferase KMT2D in BMSC osteogenesis via AKT signaling;Regenerative Therapy;2024-06

2. G-protein coupled receptor 5C (GPRC5C) is required for osteoblast differentiation and responds to EZH2 inhibition and multiple osteogenic signals;Bone;2023-11

3. Inhibition of Ezh2 redistributes bivalent domains within transcriptional regulators associated with WNT and Hedgehog pathways in osteoblasts;Journal of Biological Chemistry;2023-09

4. Novel insights of EZH2-mediated epigenetic modifications in degenerative musculoskeletal diseases;Ageing Research Reviews;2023-09

5. EZH2 can be used as a therapeutic agent for inhibiting endothelial dysfunction;Biochemical Pharmacology;2023-07

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