Normal Neurogenesis but Abnormal Gene Expression in Human Fragile X Cortical Progenitor Cells
Author:
Affiliation:
1. The Waisman Center, University of Wisconsin, Madison, WI 53705.
2. Department of Genetics, University of Wisconsin, Madison, WI 53705.
3. Departments of Anatomy and Neurology, University of Wisconsin, Madison, WI 53705.
Publisher
Mary Ann Liebert Inc
Subject
Cell Biology,Developmental Biology,Hematology
Link
https://www.liebertpub.com/doi/pdf/10.1089/scd.2007.0073
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1. Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
2. Absence of expression of the FMR-1 gene in fragile X syndrome
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4. mRNPs, polysomes or granules: FMRP in neuronal protein synthesis
5. Using human neural stem cells to model neurological disease
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