Examining the Safety, Pharmacokinetics, and Pharmacodynamics of a Rectally Administered IQP-0528 Gel for HIV Pre-Exposure Prophylaxis: A First-In-Human Study-Reference-Cited by-同舟云学术

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Examining the Safety, Pharmacokinetics, and Pharmacodynamics of a Rectally Administered IQP-0528 Gel for HIV Pre-Exposure Prophylaxis: A First-In-Human Study

Published:2021-06-01 Issue:6 Volume:37 Page:444-452
ISSN:0889-2229
Container-title:AIDS Research and Human Retroviruses
language:en
Short-container-title:AIDS Research and Human Retroviruses

Author:

Al-Khouja Amer¹,Shieh Eugenie¹,Fuchs Edward J.¹,Marzinke Mark A.¹²,Bakshi Rahul P.¹,Hummert Pamela¹,Ham Anthony S.³,Buckheit Karen W.³,Breakey Jennifer¹,Weld Ethel D.¹,Chen Huan⁴,Caffo Brian S.⁴,Buckheit Robert W.³,Hendrix Craig W.¹

Affiliation:

1. Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

2. Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

3. ImQuest BioSciences, Frederick, Maryland, USA.

4. Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Publisher

Mary Ann Liebert Inc

Subject

Infectious Diseases,Virology,Immunology

Link

https://www.liebertpub.com/doi/pdf/10.1089/aid.2020.0188

Reference35 articles.

1. Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

2. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study

3. Adherence to Nonnucleoside Reverse Transcriptase Inhibitor–Based HIV Therapy and Virologic Outcomes

4. HIV Treatment Adherence, Drug Resistance, Virologic Failure: Evolving Concepts

5. A systematic review of adherence to oral pre-exposure prophylaxis for HIV – how can we improve uptake and adherence?

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1. Tenofovir Douche as HIV Preexposure Prophylaxis for Receptive Anal Intercourse: Safety, Acceptability, Pharmacokinetics, and Pharmacodynamics (DREAM 01);The Journal of Infectious Diseases;2023-11-29

2. Ex vivo rectal tissue infection with HIV-1 to assess time to protection following oral PrEP with TDF/FTC (a sub-study of the ANRS PREVENIR study);AIDS;2023-11-16

3. Hypo-osmolar rectal douche tenofovir formulation prevents simian/human immunodeficiency virus acquisition in macaques;JCI Insight;2022-12-08

4. Bictegravir nanomicelles and anionic pullulan loaded vaginal film: Dual mechanistic pre-exposure prophylaxis (PrEP) for HIV;International Journal of Biological Macromolecules;2022-11

5. Promise, perils and cautious optimism: the next frontier in long-acting modalities for the treatment and prevention of HIV;Current Opinion in HIV and AIDS;2022-02-07

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