Minimization-Aware Recursive K*: A Novel, Provable Algorithm that Accelerates Ensemble-Based Protein Design and Provably Approximates the Energy Landscape-Reference-Cited by-同舟云学术

Minimization-Aware Recursive K*: A Novel, Provable Algorithm that Accelerates Ensemble-Based Protein Design and Provably Approximates the Energy Landscape

Published:2020-04-01 Issue:4 Volume:27 Page:550-564
ISSN:1557-8666
Container-title:Journal of Computational Biology
language:en
Short-container-title:Journal of Computational Biology

Author:

Jou Jonathan D.¹,Holt Graham T.¹²,Lowegard Anna U.¹²,Donald Bruce R.¹³⁴

Affiliation:

1. Department of Computer Science, Duke University, Durham, North Carolina.

2. Computational Biology and Bioinformatics Program, Duke University, Durham, North Carolina.

3. Department of Biochemistry, Duke University Medical Center, Durham, North Carolina.

4. Department of Chemistry, Duke University, Durham, North Carolina.

Publisher

Mary Ann Liebert Inc

Subject

Computational Theory and Mathematics,Computational Mathematics,Genetics,Molecular Biology,Modelling and Simulation

Link

https://www.liebertpub.com/doi/pdf/10.1089/cmb.2019.0315

Reference55 articles.

1. A Semidefinite Programming Approach to Side Chain Positioning with New Rounding Strategies

2. Computational structure-based redesign of enzyme activity

3. De Novo Protein Design: Fully Automated Sequence Selection

4. Rational design of proteins that exchange on functional timescales

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