Increased Progression-Free Survival with Cabozantinib Versus Placebo in Patients with Radioiodine-Refractory Differentiated Thyroid Cancer Irrespective of Prior Vascular Endothelial Growth Factor Receptor-Targeted Therapy and Tumor Histology: A Subgroup Analysis of the COSMIC-311 Study

Author:

Capdevila Jaume1,Krajewska Jolanta2,Hernando Jorge3,Robinson Bruce4,Sherman Steven I.5,Jarzab Barbara2,Lin Chia-Chi6,Vaisman Fernanda7,Hoff Ana O.8,Hitre Erika9,Bowles Daniel W.10,Williamson Denise11,Levytskyy Roman12,Oliver Jennifer13,Keam Bhumsuk14,Brose Marcia S.15

Affiliation:

1. Gastrointestinal and Endocrine Tumor Unit, Medical Oncology Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), IOB Quiron-Teknon, Barcelona, Spain.

2. Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie National Research Institute of Oncology Gliwice Branch, Gliwice, Poland.

3. Vall d'Hebron University Hospital, Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Spain.

4. Department of Medicine, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.

5. Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

6. Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.

7. Department of Endocrinology, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.

8. Department of Endocrinology, Instituto do Câncer do Estado de São Paulo, Universidade de São Paulo, São Paulo, Brazil.

9. Department of Medical Oncology, The Multidisciplinary Head and Neck Cancer Center, Országos Onkológiai Intézet, Budapest, Hungary.

10. Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

11. Department of Biostatistics, Exelixis, Inc., Alameda, California, USA.

12. Department of Medical Affairs, Exelixis, Inc., Alameda, California, USA.

13. Department of Clinical Development, Exelixis, Inc., Alameda, California, USA.

14. Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

15. Department of Medical Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Publisher

Mary Ann Liebert Inc

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

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