Effect of Deficiency of the Double-Stranded RNA-Dependent Protein Kinase, PKR, on Antiviral Resistance in the Presence or Absence of Ribonuclease L: HSV-1 Replication Is Particularly Sensitive to Deficiency of the Major IFN-Mediated Enzymes

Author:

Khabar Khalid S. A.1,Dhalla Mohammed2,Siddiqui Yunus2,Zhou Amin3,Al-Ahdal Mohammed N.2,Der Sandy D.3,Silverman Robert H.3,Williams Bryan R. G.3

Affiliation:

1. Department of Biological and Medical Research, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia and Department of Cancer Biology, Cleveland Clinic Foundation, Cleveland, OH 44195.

2. Department of Biological and Medical Research, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.

3. Department of Cancer Biology, Cleveland Clinic Foundation, Cleveland, OH 44195.

Publisher

Mary Ann Liebert Inc

Subject

Virology,Cell Biology,Immunology

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