Mapping of IFN-β Epitopes Important for Receptor Binding and Biologic Activation: Comparison of Results Achieved Using Antibody-Based Methods and Alanine Substitution Mutagenesis
Author:
Affiliation:
1. Biogen, Inc., Cambridge, MA 02142
2. Departments of Microbiology and Surgery, The Medical College of Wisconsin, Milwaukee, WI 53226
Publisher
Mary Ann Liebert Inc
Subject
Virology,Cell Biology,Immunology
Link
http://www.liebertpub.com/doi/pdf/10.1089/107999001753289541
Reference31 articles.
1. Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptors
2. Efficiency of signalling through cytokine receptors depends critically on receptor orientation
3. Atomic structure of the GCSF–receptor complex showing a new cytokine–receptor recognition scheme
4. Defining epitopes: It's not as easy as it seems
5. Comparison of a Structural and a Functional Epitope
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