Preclinical Efficacy and Safety Profile of Allometrically Scaled Doses of Doxycycline Used to Turn “On” Therapeutic Transgene Expression from High-Capacity Adenoviral Vectors in a Glioma Model-Reference-Cited by-同舟云学术

Preclinical Efficacy and Safety Profile of Allometrically Scaled Doses of Doxycycline Used to Turn “On” Therapeutic Transgene Expression from High-Capacity Adenoviral Vectors in a Glioma Model

Published:2016-06 Issue:3 Volume:27 Page:98-111
ISSN:1946-6536
Container-title:Human Gene Therapy Methods
language:en
Short-container-title:Human Gene Therapy Methods

Author:

VanderVeen Nathan¹²,Raja Nicholas¹²,Yi Elizabeth¹²,Appelman Henry³,Ng Philip⁴,Palmer Donna⁴,Zamler Daniel¹²,Dzaman Marta¹²,Lowenstein Pedro R.¹²,Castro Maria G.¹²

Affiliation:

1. Department of Neurosurgery, The University of Michigan Medical School, Ann Arbor, Michigan.

2. Department of Cell and Developmental Biology, The University of Michigan Medical School, Ann Arbor, Michigan.

3. Department of Pathology, The University of Michigan Medical School, Ann Arbor, Michigan.

4. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.

Publisher

Mary Ann Liebert Inc

Subject

Genetics (clinical),Pharmacology,Genetics,Applied Microbiology and Biotechnology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hgtb.2015.168

Reference43 articles.

1. Survival of Patients with Newly Diagnosed Glioblastoma Treated with Radiation and Temozolomide in Research Studies in the United States

2. Adenoviral vector-mediated gene therapy for gliomas: coming of age

3. Progress in gene therapy for neurological disorders

4. Immune Responses to Adenovirus and Adeno-Associated Vectors Used for Gene Therapy of Brain Diseases: The Role of Immunological Synapses in Understanding the Cell Biology of Neuroimmune Interactions

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