Transduction of Human CD34+Repopulating Cells with a Self-Inactivating Lentiviral Vector for SCID-X1 Produced at Clinical Scale by a Stable Cell Line-Reference-Cited by-同舟云学术

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Transduction of Human CD34+Repopulating Cells with a Self-Inactivating Lentiviral Vector for SCID-X1 Produced at Clinical Scale by a Stable Cell Line

Published:2012-10 Issue:5 Volume:23 Page:297-308
ISSN:1946-6536
Container-title:Human Gene Therapy Methods
language:en
Short-container-title:Human Gene Therapy Methods

Author:

Greene Michael R.¹,Lockey Timothy²,Mehta Perdeep K.³,Kim Yoon-Sang¹,Eldridge Paul W.⁴,Gray John T.¹,Sorrentino Brian P.¹

Affiliation:

1. Department of Hematology, St. Jude Children's Hospital, Memphis, TN 38105.

2. Children's GMP, LLC, St. Jude Children's Hospital, Memphis, TN 38105.

3. Hartwell Center, Bioinformatics, St. Jude Children's Hospital, Memphis, TN 38105.

4. Human Applications Laboratory, St. Jude Children's Hospital, Memphis, TN 38105.

Publisher

Mary Ann Liebert Inc

Subject

Genetics(clinical),Pharmacology,Genetics,Applied Microbiology and Biotechnology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hgtb.2012.150

Reference49 articles.

1. Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice

2. Inducible Packaging Cells for Large-scale Production of Lentiviral Vectors in Serum-free Suspension Culture

3. Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

4. Lentiviral Hematopoietic Cell Gene Therapy for X-Linked Adrenoleukodystrophy

5. Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

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