Extensive Replication of a Retroviral Replicating Vector Can Expand the A Bulge in the Encephalomyocarditis Virus Internal Ribosome Entry Site and Change Translation Efficiency of the Downstream Transgene-Reference-Cited by-同舟云学术

Extensive Replication of a Retroviral Replicating Vector Can Expand the A Bulge in the Encephalomyocarditis Virus Internal Ribosome Entry Site and Change Translation Efficiency of the Downstream Transgene

Published:2016-04 Issue:2 Volume:27 Page:59-70
ISSN:1946-6536
Container-title:Human Gene Therapy Methods
language:en
Short-container-title:Human Gene Therapy Methods

Author:

Lin Amy H.¹,Liu Yanzheng¹,Burrascano Cynthia¹,Cunanan Kathrina¹,Logg Christopher R.²,Robbins Joan M.¹,Kasahara Noriyuki²³,Gruber Harry¹,Ibañez Carlos¹,Jolly Douglas J.¹

Affiliation:

1. Tocagen Inc., San Diego, California.

2. Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California–Los Angeles, Los Angeles, California.

3. Department of Cell Biology, Miller School of Medicine, University of Miami, Miami, Florida.

Publisher

Mary Ann Liebert Inc

Subject

Genetics(clinical),Pharmacology,Genetics,Applied Microbiology and Biotechnology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hgtb.2015.131

Reference28 articles.

1. Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression