Analytical Strategies for Quantification of Adeno-Associated Virus Empty Capsids to Support Process Development
Author:
Affiliation:
1. Gene Therapy, Process Development and Biogen, Cambridge, Massachusetts.
2. Analytical Development, Biogen, Cambridge, Massachusetts.
Publisher
Mary Ann Liebert Inc
Subject
Genetics(clinical),Pharmacology,Genetics,Applied Microbiology and Biotechnology,Molecular Medicine
Link
https://www.liebertpub.com/doi/pdf/10.1089/hgtb.2019.088
Reference24 articles.
1. Adeno-associated virus-mediated gene delivery
2. Gene Therapy: Promises and Problems
3. Mechanisms of Adeno-Associated Virus Genome Encapsidation
4. A Versatile and Scalable Two-Step Ion-Exchange Chromatography Process for the Purification of Recombinant Adeno-associated Virus Serotypes-2 and -5
5. Immune Responses to Adeno-Associated Virus Vectors
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