Recombinant Manganese Peroxidase Reduces A2E Burden in Age-Related and Stargardt's Macular Degeneration Models-Reference-Cited by-同舟云学术

Recombinant Manganese Peroxidase Reduces A2E Burden in Age-Related and Stargardt's Macular Degeneration Models

Published:2018-12 Issue:6 Volume:21 Page:560-571
ISSN:1549-1684
Container-title:Rejuvenation Research
language:en
Short-container-title:Rejuvenation Research

Author:

Moody Kelsey J.¹²,Tinklepaugh Jay³,Obert Elisabeth⁴,Grohn Kris¹²,DeRosa Jennifer R.¹²,Lumen Ellie¹²,Moyer Brandon S.¹²,Campbell Scott¹²,Wolfe Aaron J.¹²,Sleeper Meegan B.¹²,Bianchi Anthony H.¹²,Fisher Cheyanne¹²,Applegate Justin¹²,Leary Emily¹²,LeClair Nicholas¹²,Wortel Danique¹²,Doyle Robert P.³,Rohrer Baerbel⁴,Blanden Adam R.¹²

Affiliation:

1. Ichor Therapeutics, Inc., Lafayette, New York.

2. Lysoclear, Inc., Lafayette, New York.

3. Department of Chemistry, Syracuse University, Syracuse, New York.

4. Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina.

Publisher

Mary Ann Liebert Inc

Subject

Geriatrics and Gerontology,Aging

Link

https://www.liebertpub.com/doi/pdf/10.1089/rej.2018.2146

Reference34 articles.

1. Lipofuscin and Macular Degeneration

2. Stargardt disease: clinical features, molecular genetics, animal models and therapeutic options

3. Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence

4. Inflammation and its role in age-related macular degeneration

5. Complement System Dysregulation and Inflammation in the Retinal Pigment Epithelium of a Mouse Model for Stargardt Macular Degeneration

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