Plasma Metabolomic Signatures of Chronic Obstructive Pulmonary Disease and the Impact of Genetic Variants on Phenotype-Driven Modules

Author:

Gillenwater Lucas A.1,Pratte Katherine A.1,Hobbs Brian D.23,Cho Michael H.23,Zhuang Yonghua4,Halper-Stromberg Eitan5,Cruickshank-Quinn Charmion6,Reisdorph Nichole7,Petrache Irina18,Labaki Wassim W.9,O'Neal Wanda K.10,Ortega Victor E.11,Jones Dean P.12,Uppal Karan12,Jacobson Sean1,Michelotti Gregory13,Wendt Christine H.14,Kechris Katerina J.4,Bowler Russell P.18

Affiliation:

1. National Jewish Health, Denver, Colorado, USA.

2. Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

3. Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

4. Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

5. Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA.

6. Agilent Technologies, Santa Clara, California, USA.

7. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

8. School of Medicine, University of Colorado, Aurora, Colorado, USA.

9. Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, Michigan, USA.

10. Lung Institute/Cystic Fibrosis Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

11. Department of Internal Medicine, Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

12. Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Emory School of Medicine, Atlanta, Georgia, USA.

13. Metabolon, Inc., Morrisville, North Carolina, USA.

14. Department of Medicine, University of Minnesota and the VAMC, Minneapolis, Minnesota, USA.

Publisher

Mary Ann Liebert Inc

Subject

General Medicine

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