The Prospective Natural History Study of Patients with Intractable Venous Malformation and Klippel–Trenaunay Syndrome to Guide Designing a Proof-of-Concept Clinical Trial for Novel Therapeutic Intervention

Author:

Fujino Akihiro1ORCID,Kuniyeda Kanako23ORCID,Nozaki Taiki4,Ozeki Michio5,Ohyama Tetsuji6,Sato Iori7,Kamibeppu Kiyoko7,Tanaka Akira23,Uemura Naoto3,Kanmuri Kazuhiro8,Nakamura Kenji8,Kobayashi Fumiaki8,Suenobu Souichi9,Nomura Tadashi10,Hayashi Ayato11,Nagao Munetomo12,Kato Aiko13,Aramaki-Hattori Noriko14,Imagawa Kotaro15,Ishikawa Kosuke16ORCID,Ochi Junko17,Horiuchi Saya4,Nagabukuro Hiroshi23

Affiliation:

1. Division of Pediatric Surgery, National Center for Child Health and Development, Setagaya-ku, Japan.

2. ARTham Therapeutics, Inc., Yakohama, Japan.

3. Department of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Oita University, Yufu, Japan.

4. Department of Radiology, St. Luke's International Hospital, Chuo-ku, Japan.

5. Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.

6. Biostatistics Center, Kurume University, Kurume, Japan.

7. Division of Health Science and Nursing, Department of Family Nursing, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Japan.

8. CTD, Inc., Chuo-ku, Japan.

9. Division of General Pediatrics and Emergency Medicine, Department of Pediatrics, Faculty of Medicine, Oita University, Yufu, Japan.

10. Department of Plastic Surgery, Kobe University Graduate School of Medicine, Hyogo, Japan.

11. Department of Plastic and Reconstructive Surgery, Juntendo University Urayasu Hospital, Urayasu, Japan.

12. Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Tohoku University, Sendai, Japan.

13. Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Oita University, Yufu, Japan.

14. Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Shinjuku-ku, Japan.

15. Department of Plastic surgery, Tokai University, Isehara, Japan.

16. Department of Plastic and Reconstructive Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

17. Department of Radiology, Suita Tokushukai Hospital, Tokushukai Medical Group, Suita, Japan.

Publisher

Mary Ann Liebert Inc

Subject

Cardiology and Cardiovascular Medicine

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