What Targets Somatic Hypermutation to the Immunoglobulin Loci?
Author:
Affiliation:
1. Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.
Publisher
Mary Ann Liebert Inc
Subject
Virology,Molecular Medicine,Immunology
Link
https://www.liebertpub.com/doi/pdf/10.1089/vim.2019.0149
Reference57 articles.
1. Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region
2. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
3. Commonality despite exceptional diversity in the baseline human antibody repertoire
4. J H 6 downstream intronic sequence is dispensable for RNA polymerase II accumulation and somatic hypermutation of the variable gene in Ramos cells
5. DNA polymerase η is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse
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