1. Department of Human Pathology, University of Messina, Messina, Sicily, Italy.
2. Department of Clinical and Experimental Medicine, University of Messina, Messina, Sicily, Italy.
3. Department of Statistics, University of Messina, Messina, Sicily, Italy.
4. Anesthesiology and Neuroreanimation Unit, University of Messina, Messina, Sicily, Italy.