Validation of an Optical Microplate Label-Free Platform in the Screening of Chemical Libraries for Direct Binding to a Nuclear Receptor-Reference-Cited by-同舟云学术

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Validation of an Optical Microplate Label-Free Platform in the Screening of Chemical Libraries for Direct Binding to a Nuclear Receptor

Published:2011-10 Issue:5 Volume:9 Page:532-548
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Vela Laura¹,Lowe Peter N.²,Gerstenmaier John³,Laing Lance G.³,Stimmel Julie B.⁴,Orband-Miller Lisa A.⁴,Martin Julio J.¹

Affiliation:

1. Screening and Compound Profiling, GlaxoSmithKline, Tres Cantos, Spain.

2. Biomolecular Interactions Consultancy, Hertford, United Kingdom.

3. SRU Biosystems, Inc., Woburn, Massachusetts.

4. Screening and Compound Profiling, GlaxoSmithKline, Research Triangle Park, North Carolina.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2010.0345

Reference30 articles.

1. The Sequence of the Human Genome

2. Biophysical Methods

3. A new strategy for improved secondary screening and lead optimization using high-resolution SPR characterization of compound-target interactions

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1. Cell-impedance-based label-free technology for the identification of new drugs;Expert Opinion on Drug Discovery;2017-03

2. Disruption of Rhodopsin Dimerization with Synthetic Peptides Targeting an Interaction Interface;Journal of Biological Chemistry;2015-10

3. Solid-Phase Biological Assays for Drug Discovery;Annual Review of Analytical Chemistry;2014-06-12

4. Strategies for membrane interaction proteomics: No mass spectrometry required;PROTEOMICS;2012-05

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