Functional Characterization and High-Throughput Screening of Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors in IMR-32 Neuroblastoma Cells
Author:
Affiliation:
1. Advanced Technology, Global Pharmaceutical Research & Development, Abbott Laboratories, Abbott Park, Illinois
2. Neuroscience Research, Global Pharmaceutical Research & Development, Abbott Laboratories, Abbott Park, Illinois.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/adt.2010.0319
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1. A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX
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4. Antisense knockdown of the rat α7 nicotinic acetylcholine receptor produces spatial memory impairment
5. AR-R 17779 improves social recognition in rats by activation of nicotinic α7 receptors
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3. GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells;Frontiers in Pharmacology;2017-02-28
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