Retroviral Transfer of Human MDR1 Gene to Hematopoietic Cells: Effects of Drug Selection and of Transcript Splicing on Expression of Encoded P-Glycoprotein-Reference-Cited by-同舟云学术

Retroviral Transfer of Human MDR1 Gene to Hematopoietic Cells: Effects of Drug Selection and of Transcript Splicing on Expression of Encoded P-Glycoprotein

Published:1999-09 Issue:13 Volume:10 Page:2173-2185
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Licht Thomas,Aran Josep M.,Goldenberg Sarah K.,Vieira Wilfred D.,Gottesman Michael M.,Pastan Ira

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/10430349950017167

Reference50 articles.

1. Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector.

2. Complete Restoration of Glucocerebrosidase Deficiency in Gaucher Fibroblasts Using a BicistronicMDRRetrovirus and a New Selection Strategy

3. Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells

4. Quantitative expression patterns of multidrug-resistance P-glycoprotein (MDR1) and differentially spliced cystic-fibrosis transmembrane-conductance regulator mRNA transcripts in human epithelia

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