A Specificity Comparison of Four Antisense Types: Morpholino, 2′-O-Methyl RNA, DNA, and Phosphorothioate DNA
Author:
Publisher
Mary Ann Liebert Inc
Subject
Pharmacology,Genetics
Link
http://www.liebertpub.com/doi/pdf/10.1089/oli.1.1997.7.151
Reference11 articles.
1. Inhibition of rabbit globin mRNA translation by sequence-specific oligodeoxyribonucleotides
2. Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides
3. Resistance of Morpholino Phosphorodiamidate Oligomers to Enzymatic Degradation
4. RNase H-mediated inhibition of translation by antisense oligodeoxyribo-nucleotides: use of backbone modification to improve specificity
5. RNase H is responsible for the non-specific inhibition ofin vitrotranslation by 2′-O-alkyl chimeric oligonucleotides: high affinity or selectivity, a dilemma to design antisense oligomers
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