Optimizing Transgene Configuration and Protein Fusions to Maximize Dopamine Production for the Gene Therapy of Parkinson's Disease-Reference-Cited by-同舟云学术

Optimizing Transgene Configuration and Protein Fusions to Maximize Dopamine Production for the Gene Therapy of Parkinson's Disease

Published:2016-09 Issue:3 Volume:27 Page:100-110
ISSN:2324-8637
Container-title:Human Gene Therapy Clinical Development
language:en
Short-container-title:Human Gene Therapy Clinical Development

Author:

Stewart Hannah J.¹,Ralph G. Scott¹,Fong-Wong Liang²,Strickland Iain²,McCloskey Laura¹,Barnes Lucy¹,Blount Ian¹,Wells Owen¹,Truran Christelle J.M.¹,Kingsman Alan J.¹,Palfi Stéphane³,Mitrophanous Kyriacos A.¹

Affiliation:

1. Oxford BioMedica (UK) Ltd., Oxford, United Kingdom

2. Henry Wellcome L.I.N.E., University of Bristol, Bristol BS1 3NY, United Kingdom

3. AP-HP, Groupe Hospitalier Henri-Mondor, DHU PePsy, Neurochirurgie, INSERM IMRB U955 eq.14, Université Paris Est Créteil (UPEC), Faculté de Médecine, Creteil, F-94010, France.

Publisher

Mary Ann Liebert Inc

Subject

Genetics(clinical)

Link

http://www.liebertpub.com/doi/pdf/10.1089/humc.2016.056

Reference28 articles.

1. Parkinson's Disease

2. Modulation of Striatal Projection Systems by Dopamine

3. Dopamine Agonists in the Treatment of Parkinsons Disease-Past, Present and Future

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