Halide Ion Effects on HumanEther-à-go-goRelated Gene Potassium Channel Properties
Author:
Affiliation:
1. Safety Assessment and Laboratory Animal Resources, Merck Research Laboratories, West Point, Pennsylvania.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/adt.2013.531
Reference18 articles.
1. A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel
2. HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family
3. QT-interval prolongation by non-cardiac drugs: lessons to be learned from recent experience
4. Safety of Non-Antiarrhythmic Drugs that Prolong the QT Interval or Induce Torsade de Pointes
5. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
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