Disease-Regulated Gene Therapy with Anti-Inflammatory Interleukin-10 Under the Control of the CXCL10 Promoter for the Treatment of Rheumatoid Arthritis
Author:
Affiliation:
1. Experimental Rheumatology, Radboud University Medical Center, Nijmegen, The Netherlands.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hum.2015.127
Reference38 articles.
1. An inflammation-inducible adenoviral expression system for local treatment of the arthritic joint
2. Gene transfer to human joints: Progress toward a gene therapy of arthritis
3. Safety, Tolerability, and Clinical Outcomes after Intraarticular Injection of a Recombinant Adeno-associated Vector Containing a Tumor Necrosis Factor Antagonist Gene: Results of a Phase 1/2 Study
4. Local delivery of a recombinant adenoassociated vector containing a tumour necrosis factor antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study
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