Rat Liver Cytochrome P450IA2 Synthesized by Transfected COS-1 Cells Efficiently Activates Food-Derived Promutagens
Author:
Publisher
Mary Ann Liebert Inc
Subject
Cell Biology,Genetics,Molecular Biology,General Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/dna.1991.10.33
Reference22 articles.
1. cDNA Clones for Liver Cytochrome P-450s from Individual Aroclor-Treated Rats: Constitutive Expression of a New P-450 Gene Related to Phenobarbital-Inducible Forms
2. Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test
3. Mutagen activation by cDNA-expressed P1450, P3450, and P450a
4. Expression of P1-450 and P3-450 DNA coding sequences as enzymatically active cytochromes P-450 in mammalian cells.
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1. Recombinant human P450 forms 1A1, 1A2, and 1B1 catalyze the bioactivation of heterocyclic amine mutagens inEscherichia coli lacZ strains;Environmental and Molecular Mutagenesis;2001
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3. New proteins in the rat CYP2B subfamily: Presence in liver microsomes of the constitutive CYP2B3 protein and the phenobarbital-inducible protein product of alternatively spliced CYP2B2 mRNA;Biochemical Pharmacology;1996-10
4. Rat Liver Cytochrome P450 2B3: Structure of theCYP2B3Gene and Immunological Identification of a Constitutive P450 2B3-Like Protein in Rat Liver;DNA and Cell Biology;1994-08
5. Inhibition of NAD(P)H: Quinone oxidoreductase1 in ethacrynic acid-resistant human colon carcinoma cells;Biochemical Pharmacology;1994-06
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