Nonlinear Disposition and Metabolic Interactions of Cannabidiol Through CYP3A Inhibition In Vivo in Rats-Reference-Cited by-同舟云学术

Nonlinear Disposition and Metabolic Interactions of Cannabidiol Through CYP3A Inhibition In Vivo in Rats

Published:2020-12-01 Issue:4 Volume:5 Page:318-325
ISSN:2578-5125
Container-title:Cannabis and Cannabinoid Research
language:en
Short-container-title:Cannabis and Cannabinoid Research

Author:

Nagao Michiru¹,Nakano Yukako¹,Tajima Masataka¹,Sugiyama Erika¹,Sato Vilasinee Hirunpanich²,Inada Makoto³,Sato Hitoshi¹

Affiliation:

1. Division of Pharmacokinetics and Pharmacodynamics, Department of Pharmacology, Toxicology and Therapeutics, School of Pharmacy, Showa University, Tokyo, Japan.

2. Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.

3. Development Department Diagnostic Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan.

Publisher

Mary Ann Liebert Inc

Subject

Pharmacology (medical),Complementary and alternative medicine,Pharmacology

Link

https://www.liebertpub.com/doi/pdf/10.1089/can.2019.0098

Reference31 articles.

1. 1. World Health Organization Expert Committee on Drug Dependence. Cannabidiol (CBD) Pre-review Report Agenda Item 5.2 and Peer Review. World Health Organization: Geneva, Switzerland, 2017.

2. Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor

3. Agonistic Properties of Cannabidiol at 5-HT1a Receptors

4. Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors

5. Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide

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