HTS Identifies Novel and Specific Uncompetitive Inhibitors of the Two-Component NS2B-NS3 Proteinase of West Nile Virus-Reference-Cited by-同舟云学术

HTS Identifies Novel and Specific Uncompetitive Inhibitors of the Two-Component NS2B-NS3 Proteinase of West Nile Virus

Published:2007-12 Issue:6 Volume:5 Page:737-750
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Johnston Paul A.¹,Phillips Jennifer¹,Shun Tong Ying¹,Shinde Sunita¹,Lazo John S.¹,Huryn Donna M.¹²³,Myers Michael C.³,Ratnikov Boris I.⁴,Smith Jeffrey W.⁴,Su Ying⁴⁵,Dahl Russell⁴⁵,Cosford Nicholas D.P.⁴⁵,Shiryaev Sergey A.⁴,Strongin Alex Y.⁴

Affiliation:

1. Pittsburgh Molecular Library Screening Center, Department of Pharmacology, University of Pittsburgh Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA.

2. Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA.

3. The Penn Center for Molecular Discovery, University of Pennsylvania, Philadelphia, PA.

4. Burnham Institute for Medical Research, La Jolla, CA.

5. San Diego Center for Chemical Genomics, Burnham Institute for Medical Research, La Jolla, CA.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2007.101

Reference32 articles.

1. Recent Advances in the Molecular Biology of West Nile Virus