Induced CD20 Expression on B-Cell Malignant Cells Heightened the Cytotoxic Activity of Chimeric Antigen Receptor Engineered T Cells-Reference-Cited by-同舟云学术

Induced CD20 Expression on B-Cell Malignant Cells Heightened the Cytotoxic Activity of Chimeric Antigen Receptor Engineered T Cells

Published:2019-04-01 Issue:4 Volume:30 Page:497-510
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Xu Yingxi¹,Li Saisai¹,Wang Ying¹,Liu Jia¹,Mao Xinhe¹,Xing Haiyan¹,Tian Zheng¹,Tang Kejing¹,Liao Xiaolong¹,Rao Qing¹,Xiong Dongsheng¹,Wang Min¹,Wang Jianxiang¹

Affiliation:

1. State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

https://www.liebertpub.com/doi/pdf/10.1089/hum.2018.119

Reference48 articles.

1. The Biological Activity of Human CD20 Monoclonal Antibodies Is Linked to Unique Epitopes on CD20

2. Genetic and Epigenetic Modulation of CD20 Expression in B-Cell Malignancies: Molecular Mechanisms and Significance to Rituximab Resistance

3. A unique cell surface antigen identifying lymphoid malignancies of B cell origin.

4. The use of novel monoclonal antibodies in the treatment of acute lymphoblastic leukemia

5. Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell–mediated B-cell cytotoxicity

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